Detecting and mitigating Advanced Persistent Threats (APTs) requires a comprehensive approach involving technology, processes, and human vigilance. Network traffic analysis is crucial, employing anomaly detection to spot unusual patterns like unexpected data transfers or off-hours activity and using deep packet inspection to analyze packet content for malicious signs.

Endpoint Detection and Response (EDR) tools monitor endpoints for suspicious activities, providing real-time alerts and forensic capabilities.

Threat intelligence is essential; integrating feeds about known threats helps identify and respond to APT indicators. User and Entity Behavior Analytics (UEBA) tracks typical behavior, flagging deviations that might indicate an APT presence.

Security Information and Event Management (SIEM) systems aggregate and analyze logs from various sources, offering a centralized view to detect and correlate potential threats.

Mitigation involves network segmentation to limit lateral movement, regular software updates and patch management to close vulnerabilities, and application whitelisting to restrict unauthorized software execution.

User education and training ensure that employees recognize phishing attempts and other social engineering tactics. Finally, having a robust incident response plan allows for swift action to contain and eradicate threats, minimizing potential damage.