What are the latest advancements in CRISPR-Cas9 technology, and how are they being applied in gene therapy?
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CRISPR-Cas9 technology has rapidly evolved since its inception. Recent advancements include base editing, which can change single DNA letters without cutting the DNA strand, and prime editing, offering more precise and versatile gene editing. These techniques hold immense promise for treating genetic diseases.
In gene therapy, CRISPR-Cas9 is being explored to correct faulty genes causing conditions like sickle cell disease, cystic fibrosis, and Huntington’s disease. By delivering the CRISPR system to specific cells, scientists aim to edit the disease-causing gene and restore normal function. Additionally, CRISPR is being used to develop new immunotherapies by modifying immune cells to better fight cancer. While challenges remain, the potential of CRISPR-Cas9 in revolutionizing medicine is undeniable.