How we can curate cancer by use any genetic tool? Give the Example where genetic tool has used to cure disease?
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On: December 6, 2024
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Daily Answer Writing Practice Questions (6 December 2024)
What factors influence the location of manufacturing industries in India? Discuss the key industrial regions of the country. (Answer in 200 words) भारत में विनिर्माण उद्योगों की स्थान चयन को प्रभावित करने वाले प्रमुख कारक कौन-कौन से हैं? साथ ही, ...
On: December 5, 2024
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Daily Answer Writing Practice Questions (5 December 2024)
What are the factors influencing the location of the jute industry in India? Highlight the key challenges faced by this industry.(Answer in 200 words) भारत में जूट उद्योग की अवस्थिति पर प्रभाव डालने वाले कारकों की सूची बनाइए और इस ...
On: December 4, 2024
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Daily Answer Writing Practice Questions (4 December 2024)
Provide a concise description of the erosional and depositional landforms formed by glacier movement. (Answer in 200 words) हिमनदों के संचलन से उत्पन्न विभिन्न अपरदित और निक्षेपित भू-आकृतियों का संक्षेप में वर्णन कीजिए। (उत्तर 200 शब्दों में दें)
CRISPR-Cas9 gene editing illustration
The use of genetic tools to treat cancer represents an exciting advancement in medical science. One of the most notable tools is CRISPR-Cas9, a cutting-edge gene-editing technology that allows scientists to precisely change DNA within cells. CRISPR-Cas9 can target and correct specific genetic mutations that cause cancer, offering a new approach to treatment.
For example, CRISPR-Cas9 has been used to modify immune cells called T cells. Researchers edit these cells to better recognize and attack cancer cells. These enhanced T cells are then put back into the patient’s body, where they can more effectively target and destroy cancerous cells. This approach, known as CAR-T cell therapy, has shown promising results, especially in treating blood cancers like leukemia and lymphoma.
Another genetic tool, RNA interference (RNAi), can turn off specific genes that help cancer grow. By introducing small molecules called siRNAs into cancer cells, scientists can reduce the activity of genes that promote tumor growth. This method is being tested in clinical trials for various cancers, including liver cancer.
In summary, genetic tools like CRISPR-Cas9 and RNA interference offer new and promising ways to treat cancer. These technologies allow for precise targeting and modification of genetic material, paving the way for personalized and effective cancer treatments. Ongoing research and clinical trials highlight the potential of these tools to revolutionize cancer therapy and improve outcomes for patients.
Genetic tools, particularly CRISPR-Cas9, hold promise for curing cancer by editing genes associated with tumor growth and resistance. CRISPR-Cas9 can target and modify specific DNA sequences within cancer cells, potentially correcting mutations or silencing oncogenes that drive cancer progression.
Example: In a groundbreaking case, researchers used CRISPR to treat a patient with metastatic lung cancer. The patient’s T-cells were extracted, genetically edited using CRISPR to enhance their ability to recognize and attack cancer cells, and then reintroduced into the patient’s body. This personalized immunotherapy approach showed promising results in targeting and reducing cancerous tumors.
Additionally, CAR-T cell therapy, which involves genetically modifying a patient’s T-cells to express chimeric antigen receptors (CARs) that specifically target cancer cells, has shown success in treating certain types of leukemia and lymphoma. For example, the FDA-approved CAR-T therapy, Kymriah, has demonstrated high remission rates in patients with refractory or relapsed acute lymphoblastic leukemia.
These examples illustrate the potential of genetic tools to revolutionize cancer treatment by providing targeted, personalized therapies that can effectively combat the disease.