Transgenic animals: what are they? Include a note with appropriate justifications on their applications. [Answer Limit: 250 words] [UKPSC 2012]
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Transgenic animals are organisms that have been genetically modified to contain one or more foreign genes inserted into their genomes. This modification is achieved through techniques such as gene transfer, allowing the expression of specific traits that do not occur naturally in the species.
### Applications of Transgenic Animals:
1. **Biomedical Research**: Transgenic animals, especially mice, are widely used as models for human diseases. For instance, genetically modified mice can replicate conditions such as cancer, diabetes, or Alzheimer’s disease, facilitating the study of disease mechanisms and testing new therapies.
2. **Pharmaceutical Production**: Certain transgenic animals can produce valuable pharmaceuticals. For example, genetically engineered goats can produce milk containing therapeutic proteins, such as antithrombin, which is used to treat blood clotting disorders. This biopharmaceutical production is often more efficient and cost-effective than traditional methods.
3. **Agricultural Benefits**: Transgenic animals can be developed to improve livestock traits. For instance, genetically modified cows may produce milk with enhanced nutritional content or resistance to diseases, thus increasing productivity and sustainability in dairy farming.
4. **Environmental Applications**: Transgenic animals, such as modified mosquitoes, can be designed to reduce the spread of diseases like malaria. By introducing genes that inhibit reproduction or transmission of parasites, these modifications can help control disease vectors.
### Conclusion:
Transgenic animals hold significant potential across various fields, including medicine, agriculture, and environmental management. Their ability to express desired traits enhances research capabilities, improves production efficiencies, and can contribute to solving pressing health and ecological issues. However, ethical considerations and regulatory frameworks must be established to govern their use responsibly.