Mandalien disorders :

●It is a genetics disorder

●Chromosomes does not changes

●Only single gene is involved

●Cause mutation in single gene

●Also called as monotonic disorder

●Either dominant or recessive

EX:

1.Haemophilia

2.sickle cell anemia

3.phenylketonuria

4.color blindness

5.thalassemia

6.cystic fibrosis

Non-mendelian disorder :

●It is a genetic disorder

●Cause error in cell division following meiosis and mitosis

●Chromosomes changes

●More than one gene is involved

●called as chromosomal disorder Neither dominant or recessive

EX:

1.Allosomal disorder

a.Klinefelter’s syndrome

b.Turner’s syndrome

2.Autosomal disorder

a .Down syndrome

b.Edwards syndrome

c.Patau syndrome

d.Cri-du-chat syndrome