Pregnant women diagnosed with sickle cell disease (SCD) face various complications that can significantly affect their health and pregnancy outcomes.

Types of Complications:
1. **Vaso-Occlusive Crises:** These painful episodes occur due to sickle-shaped cells blocking blood flow, leading to acute pain and requiring medical intervention.
2. **Infections:** Increased susceptibility to infections, particularly urinary tract infections and pneumonia, can complicate pregnancy and may require antibiotic treatment.
3. **Anemia:** Pregnant women with SCD may experience exacerbated anemia, leading to fatigue and increased risk of complications for both mother and baby.
4. **Preterm Birth:** There is a higher risk of preterm labor and delivery due to the various health challenges associated with SCD.
5. **Preeclampsia:** Women with SCD may have an increased risk of developing preeclampsia, a serious condition characterized by high blood pressure and organ dysfunction.

Subsequent Pregnancy Outcomes:
– **Low Birth Weight:** Babies born to mothers with SCD are more likely to have low birth weight, which can lead to long-term health issues.
– **Neonatal Complications:** There may be a higher incidence of neonatal complications, including increased risk of stillbirth.
– **Maternal Morbidity:** Women with SCD are at greater risk for maternal complications, which can affect long-term health outcomes.

Conclusion:
Overall, pregnant women with sickle cell disease face a range of complications that can impact both maternal and fetal health, necessitating comprehensive prenatal care and monitoring to optimize outcomes.