Solexa sequencing, now known as Illumina sequencing, is a next-generation sequencing technology known for its high-throughput capabilities and accuracy. Key features include:

1. Bridge Amplification: DNA fragments are attached to a flow cell and amplified to form clusters through a process called bridge amplification, resulting in numerous copies of each fragment.
2. Reversible Terminator Chemistry: Incorporates reversible terminator nucleotides, which allows for the addition of one nucleotide at a time, ensuring accurate base incorporation and high sequencing fidelity.
3. Massive Parallel Sequencing: Sequences millions of DNA fragments simultaneously, providing high-throughput data generation suitable for large-scale genomic studies.
4. Short Read Lengths: Typically generates short reads, around 50-300 base pairs, which are suitable for various applications like genome resequencing, transcriptome analysis, and DNA methylation studies.
5. Fluorescent Labeling: Uses fluorescently labeled nucleotides for detection. Each base (A, T, C, G) is labeled with a different fluorophore, allowing for real-time base calling as nucleotides are incorporated.
6. High Accuracy and Sensitivity: Offers high accuracy due to precise base calling and the ability to sequence low input amounts of DNA, making it suitable for applications requiring detailed genetic analysis.
7. Cost-Effectiveness: Provides a cost-effective solution for large-scale sequencing projects, with decreasing costs per base sequenced over time.

These features make Solexa/Illumina sequencing a cornerstone of modern genomic research.