Synthetic biology is an advanced field that combines biology and engineering to design and construct new biological systems, or to redesign existing biological systems for useful purposes. Unlike traditional genetic engineering, which typically involves modifying existing organisms by adding or alteRead more
Synthetic biology is an advanced field that combines biology and engineering to design and construct new biological systems, or to redesign existing biological systems for useful purposes. Unlike traditional genetic engineering, which typically involves modifying existing organisms by adding or altering a few genes, synthetic biology often involves creating entirely new genetic sequences from scratch.
Synthetic biology takes a more systematic and engineering-based approach, aiming to create standardised biological components that can be assembled in a modular way. The most notable example of synthetic biology can be shown in the synthetic yeast project. In this project, the researchers aim to create the entire yeast genome in the lab and are successful in creating 7 out of 16 chromosomes entirely in lab.
Traditional genetic editing involves modifying existing organisms by altering or adding specific genes to achieve desired traits or functions. This approach is focused on making targeted changes to the genetic makeup of an organism to enhance specific traits or functions. On the other hand, synthetic biology takes a broader approach by designing and constructing new biological systems.
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Advancements in biotechnology, particularly CRISPR-Cas9 gene editing and synthetic biology, offer revolutionary possibilities for addressing global health challenges and enhancing human longevity. CRISPR-Cas9: This gene-editing tool allows precise modifications of DNA, enabling the correction of genRead more
Advancements in biotechnology, particularly CRISPR-Cas9 gene editing and synthetic biology, offer revolutionary possibilities for addressing global health challenges and enhancing human longevity.
CRISPR-Cas9: This gene-editing tool allows precise modifications of DNA, enabling the correction of genetic defects responsible for diseases like cystic fibrosis, sickle cell anemia, and certain cancers. By targeting and repairing faulty genes, CRISPR-Cas9 has the potential to cure inherited disorders and prevent their transmission to future generations.
Synthetic Biology: This field involves designing and constructing new biological parts, devices, and systems. It can lead to the development of novel treatments, such as engineered bacteria that produce therapeutic compounds or synthetic cells that target and destroy cancer cells. Additionally, synthetic biology can create bioengineered tissues and organs for transplantation, addressing the shortage of donor organs.
Ethical Considerations:
- Safety and Unintended Consequences: Off-target effects and long-term impacts of gene editing need thorough evaluation to prevent harm.
- Equity and Access: Ensuring these advanced treatments are accessible to all, not just the wealthy, is crucial for global health equity.
- Germline Editing: Editing genes in embryos raises concerns about designer babies and long-term effects on the human gene pool.
- Consent and Autonomy: Patients must have informed consent, understanding the risks and benefits of these biotechnologies.
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