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Explain the process of replication in Eukaryotes in detail
The process of replication in eukaryotes involves the following steps: 1. Initiation: - The origin recognition complex (ORC) binds to the origin of replication. - The Mcm complex is recruited, and the double helix is unwound by helicases. 2. Unwinding: - The double helix is unwound byRead more
The process of replication in eukaryotes involves the following steps:
1. Initiation:
– The origin recognition complex (ORC) binds to the origin of replication.
– The Mcm complex is recruited, and the double helix is unwound by helicases.
2. Unwinding:
– The double helix is unwound by helicases, creating a replication fork.
– Topoisomerase relaxes the tension in the DNA.
3. Synthesis:
– DNA polymerase alpha (Pol α) begins synthesizing the leading strand.
– DNA polymerase delta (Pol δ) synthesizes the lagging strand in short, discontinuous segments (Okazaki fragments).
4. Elongation:
– The leading strand is continuously synthesized.
– The lagging strand is synthesized in short segments, which are later joined.
5. Ligation:
– DNA ligase seals the gaps between the Okazaki fragments, forming a continuous strand.
6. Proofreading and editing:
– DNA polymerase and other enzymes correct errors and ensure the new DNA is error-free.
7. Completion:
– The replication fork closes, and the new DNA molecule is complete.
8. Separation:
– The replicated chromosomes separate, each containing a complete copy of the genetic material.
This process is regulated by various proteins and enzymes, ensuring accurate and efficient replication of eukaryotic DNA.
See lessExplain the process of replication in Eukaryotes in detail
The process of replication in eukaryotes involves the following steps: 1. Initiation: - The origin recognition complex (ORC) binds to the origin of replication. - The Mcm complex is recruited, and the double helix is unwound by helicases. 2. Unwinding: - The double helix is unwound byRead more
The process of replication in eukaryotes involves the following steps:
1. Initiation:
– The origin recognition complex (ORC) binds to the origin of replication.
– The Mcm complex is recruited, and the double helix is unwound by helicases.
2. Unwinding:
– The double helix is unwound by helicases, creating a replication fork.
– Topoisomerase relaxes the tension in the DNA.
3. Synthesis:
– DNA polymerase alpha (Pol α) begins synthesizing the leading strand.
– DNA polymerase delta (Pol δ) synthesizes the lagging strand in short, discontinuous segments (Okazaki fragments).
4. Elongation:
– The leading strand is continuously synthesized.
– The lagging strand is synthesized in short segments, which are later joined.
5. Ligation:
– DNA ligase seals the gaps between the Okazaki fragments, forming a continuous strand.
6. Proofreading and editing:
– DNA polymerase and other enzymes correct errors and ensure the new DNA is error-free.
7. Completion:
– The replication fork closes, and the new DNA molecule is complete.
8. Separation:
– The replicated chromosomes separate, each containing a complete copy of the genetic material.
This process is regulated by various proteins and enzymes, ensuring accurate and efficient replication of eukaryotic DNA.
See lesswomen
Counteracting negative stereotypes of feminism in the workplace involves education, dialogue, and leadership commitment. Here are some effective strategies: Education and Training: Offer workshops and training sessions that clarify what feminism truly stands for—gender equality, not female superioriRead more
women
Counteracting negative stereotypes of feminism in the workplace involves education, dialogue, and leadership commitment. Here are some effective strategies: Education and Training: Offer workshops and training sessions that clarify what feminism truly stands for—gender equality, not female superioriRead more
women
Counteracting negative stereotypes of feminism in the workplace involves education, dialogue, and leadership commitment. Here are some effective strategies: Education and Training: Offer workshops and training sessions that clarify what feminism truly stands for—gender equality, not female superioriRead more
women
Counteracting negative stereotypes of feminism in the workplace involves education, dialogue, and leadership commitment. Here are some effective strategies: Education and Training: Offer workshops and training sessions that clarify what feminism truly stands for—gender equality, not female superioriRead more
women
Counteracting negative stereotypes of feminism in the workplace involves education, dialogue, and leadership commitment. Here are some effective strategies: Education and Training: Offer workshops and training sessions that clarify what feminism truly stands for—gender equality, not female superioriRead more
women
Counteracting negative stereotypes of feminism in the workplace involves education, dialogue, and leadership commitment. Here are some effective strategies: Education and Training: Offer workshops and training sessions that clarify what feminism truly stands for—gender equality, not female superioriRead more
women
Counteracting negative stereotypes of feminism in the workplace involves education, dialogue, and leadership commitment. Here are some effective strategies: Education and Training: Offer workshops and training sessions that clarify what feminism truly stands for—gender equality, not female superioriRead more