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What are transgenic animals? How are they created?
Transgenic means the genes that have been altered or changed their basic characteristics in the germ line are termed as Transgenic. The animals that have been co-focused with transgenic genes are known as transgenic animals. Lately, many domestic animals such as Transgenic cows, bulls, sheep, goatsRead more
Transgenic means the genes that have been altered or changed their basic characteristics in the germ line are termed as Transgenic. The animals that have been co-focused with transgenic genes are known as transgenic animals.
Lately, many domestic animals such as Transgenic cows, bulls, sheep, goats, hens, etc have been converted into Trangenic animals for maximum yield for human development as well as for eliminating any specific characteristics that are harmful to the animal.
The following steps are required to convert an animal into Transgenics-
a) Targeted gene extraction
b) Conversion of the genome into desired characteristics by incorporating transgenic genes into the inner cell mass (ICM) of the genome.
c) Embryo transfer into the targeted animal
d) Offspring testing
e) Demonstrating the transgenic gene in the animal.
Transgenic genes can be carried by the oocyte or sperm via various carriers. some of the most compatible carriers used in the fields are retroviruses or rotaviruses.
Applications-
a) Transgenics are used to eliminate the disease genes present in the targeted animal for an enhanced quality of life and their upcoming generations.
b) Produce disease-free, high-yielding, and excellent characteristics in the targeted animal.
For example- Molly, a transgenic sheep was incorporated with a high-yielding transgenic gene for more quality production of wool.