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Name the three consecutive days without considering the weekdays
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What are the key challenges faced by Women who choose to restart their careers after a long break and how can organisations support their reintegration into the workforce?
Restarting career after a long break imposes many challenges on women. One of the biggest challenge is the loss of professional network. They often loose touch with former colleagues, mentors and contacts in the industry. This makes it difficult for them to access job opportunities. They don't get rRead more
Restarting career after a long break imposes many challenges on women. One of the biggest challenge is the loss of professional network. They often loose touch with former colleagues, mentors and contacts in the industry. This makes it difficult for them to access job opportunities. They don’t get recommendations or referrals. It takes time to rebuild contacts.
Moreover, repid technological evolution requires continuous learning. Women who have been away from the workplace for years feel out touch or lacking in current skills.
Employers often assume that candidates with resume gaps lack lack commitment or current skills. This bias often reflects in less interview call backs and lower salary offers, despite the candidate’s potential and qualifications.
Another challenge that they face is lack of self confidence. They may doubt their qualifications and abilities, especially if their experience workplace discrimination before the break.
Balancing family responsibilities is another big challenge for many women returning to work. Juggling household duties, childcare with career demands impact their decisions to restart their careers.
Last but not the least, family pressures may discourage women from pursuing ambitious career goals or returning to full time employment.
Can someone explain to me the process of DNA translation in easy words?
DNA Translation is the process of protein synthesis using mRNA molecules as templates. In general, gene expression is the process by which gene manufactures it's corresponding protein. This process occurs in two steps: first, genetic information in DNA is converted into mRNA by way of transcription.Read more
DNA Translation is the process of protein synthesis using mRNA molecules as templates.
In general, gene expression is the process by which gene manufactures it’s corresponding protein. This process occurs in two steps: first, genetic information in DNA is converted into mRNA by way of transcription. Secondly, the resulting mRNA which is the single stranded copy of the gene is translated into protein.
Translation and occurs within specialised organelles called ribosomes, which are composed of two subunits, larger 50 S subunit and smaller 30S subunit. Ribosomes contain proteins and specialised rNA molecules called tRNA and mRNA and proteins.
This process occurs as:
Why don't we have exact medicines to cure viral disease ,un like bacterial or ,fungal,and protozoal infections,which have specific treatment?
Developing exact medicines to cure viral diseases is challenging as compared to bacterial, fungal or protozoal diseases is due to the unique nature of viruses. Some of the key challenges are: 1) Viruses require host cells ton replicate. They hijack host's cellular machinery for their own replicationRead more
Developing exact medicines to cure viral diseases is challenging as compared to bacterial, fungal or protozoal diseases is due to the unique nature of viruses.
Some of the key challenges are:
1) Viruses require host cells ton replicate. They hijack host’s cellular machinery for their own replication. Thus it is difficult to target viruses without harming the hosts which they infect.
2) The drugs particularly antibiotics that are used to target bacteria work on the differences in the metabolic pathway or cellular structures between bacteria and human. But viruses lack a metabolic pathway or cellular structures that can be targetted by drugs.
3) Some viruses can persist in the body for extensive periods. Thus they may evade immune responses and antiviral drugs during persistent phases.
4) Immune response to viral infection varies between people. Thus, developing drugs that enhance immune response to effectively treat viral infections without any harmful side effects is a challenging task.
See lessHow does recombinant DNA technology contribute to the production of insulin?
Recombinant insulin was the first recombinant medicine to be used in the USA. It was first produced in 1983 by American Biotech Company. It's trademark name is Humulin. Recombinant DNA Technology allows for the production of insulin in bacterial or yeast cells. This is done by inserting human insuliRead more
Recombinant insulin was the first recombinant medicine to be used in the USA. It was first produced in 1983 by American Biotech Company. It’s trademark name is Humulin.
Recombinant DNA Technology allows for the production of insulin in bacterial or yeast cells. This is done by inserting human insulin gene into these cells which then produce insulin, identical to naturally occuring insulin, which reduces the risk of allergic reactions and immune responses. It is also free from contaminants and impurities that may be present in animal-derived insulin.
The following steps are involved in the production of recombinant insulin:
Step 1: Insulin gene is isolated from human DNA, which encodes the sequence of amino acids that make up insulin protein.
Step 2: Isolated gene is inserted into plasmid or viral vector. The vector contains regulatory sequences that control expression of this gene in the host.
Step 3: Recombinant vector carrying insulin gene is introduced into host cells.
Step 4: Host cells begin to express insulin gene.
Step 5: Inside the host, insulin gene is transcribed into mRNA and then translated into insulin protein.
Step 6: Host cells are grown in fermentation tanks to optimize insulin production.
Step 7: Insulin is then harvested and purified from the cell culture.
See lessGene Therapy
Genome Editing is a process by which alterations are made to the DNA (genetic material) of an organism. These genetic alterations can cause changes in physical traits like hair colour, eye colour, body height, etc. Editing can be done on somatic cells as well as germline cells. This process has manyRead more
Genome Editing is a process by which alterations are made to the DNA (genetic material) of an organism. These genetic alterations can cause changes in physical traits like hair colour, eye colour, body height, etc. Editing can be done on somatic cells as well as germline cells. This process has many prospects for example, it can be used to prevent, treat or cure certain diseases.
Inspite of the benefits this technology offers, there are various ethical issues involved.
Some concerns are:
1) Some arguments say that when germline genome is edited, there is alteration in the genome of embryo at its earliest stages, which may effect every cell. This means that it has an impact not only on the person who may result, but also on his/her descendants.
2) Should people be allowed to use this technology to embrace basic human characteristics like height or skin colour?
3) It is difficult to ensure that people completely understand the risks and benefits involved with altering their genome.
4) The high cost of genome editing may make it available only to the wealthy section of society, thus ensuring fair and equitable access is a big challenge.
5) Genetically engineered humans may feel alienated from themselves or feel a confused identity.
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